TFF-MV- tangential flow filter for large EV separation and recovery

TFF-MV – tangential flow filtration-based device

Sample type

Diluted EV containing matrices (i.e. urine, conditioned cell media)

Quantity

1 concentrator

Product overview

TFF-MV is a filter cartridge in hollow fibers made of polysulfone. The filter is very useful for separating different EVs by size. Indeed, microvesicles bigger than 150 nm are retained inside the hollow fibers, while small EVs and molecules easily permeate the filter. Microvesicles can be recovered with a syringe in PBS buffer without additional purification steps.

Filter cartridge

Polysulfone hollow fibres

Sample volume per reaction

Recommended sample volume from 10 ml up to several liters if connected to mechanical pump.

EV recovery

83%

Concentration time

From 5 minutes

Reusable

Up to 20 times

Applications

Separation of EVs by size.

Recovering of big microvesicles in one step, without additional purification.