Heparin and Low Molecular Weight Heparin
Heparin (cat # HEP001) has an average molecular weight of about 15 kDa it is highly polydisperse with a considerable spread of mol wts.
LMW Heparin is made via partial digestion of heparin with heparinase I, it is less polydisperse than the heparin it is made from (HEP001) with a molecular weight range of 1800 – 7500 daltons.
The profiles below a comparison between the partially digested LMW Heparin and the parent Heparin. The arrows show elution positions of a heparin hexasaccharide dp6 (mol wt 1800) and a heparin dp24 (mol wt 7200) main peak in heparin polymer (23 mins) corresponds to a mol wt of approx 14Kda