Selectively Desulphated Heparin Oligosaccharides
Heparin oligosaccharides made by partial digestion of high quality heparin modified by standard chemical methods to selectively remove the sulphate groups.
Investigate the specific protein binding motifs in Heparin and HS GAGs. Use these products in conjunction with our heparin oligosaccharides and HepMers to investigate the essential functional groups and specific oligosaccharide chain length required for high affinity/optimal protein interactions.
4 variations of selectively desulphated heparin oligosaccharides are available, dp4 – dp12:
2-O-desulphated heparin oligosaccharides Sulphate group removed from the C2 of iduronate
6-O-desulphated heparin oligosaccharides Sulphate group removed from the C6 of glucosamine
N-desulphated heparin oligosaccharides Sulphate group removed from the N sulphate of the glucoasmine
N-desulphated re N-acetylated heparin oligosaccharides The free amino group (NH 3) in N-desulphated heparin has been modified by acetylation